Pathogenesis of diseases like cancer, allergies, viral or bacterial infections, diabetic infections, inflammation, autoimmune conditions etc. in vertebrates is directly linked to the immune dysfunction or imbalance of immune system co-ordination. And an approach for the prophylaxis, treatment and control of such immunity related diseases is immunomodulation. We aim to identify potential immunomodulatory compounds form Bangladeshi medicinal plants and derivatization of active components by using dioxoruthenium (VI) tetraphenyl porphyrin based biomimetic oxidation system as reported by Kishor et. al. as well as to identify active pharmacophore through their structure activity relationship study.